FOI release

Freedom of Information request: Myodil

Case reference FOI2025/01339

Received 30 December 2025

Published 5 February 2026

Request

I am making a request under the Freedom of Information Act 2000 regarding the oil-based contrast agent Myodil (Pantopaque) and similar agents (e.g., oil-based contrast media used for myelography) Please could you confirm: 1. Whether Myodil, Pantopaque, or oil-based contrast media were licensed or in clinical use in the UK in 1986. 2. When their use ceased or was formally discontinued or discouraged in the UK. 3. Whether the MHRA or its predecessor bodies issued guidance (including archived or superseded guidance) describing specific procedural requirements for their use, such as post-procedure patient positioning (for example, being kept upright or advised not to lie flat). This request is limited to regulatory status and guidance held by the MHRA or its predecessor bodies and does not seek patient- or hospital-specific information.

Response

See attached

Documents

• FOI2025_01339 (redacted).pdf (690.4 KB)

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