FOI release

mental health side effects from unlicensed endometriosis treatment

Some or all of the information requested may not have been provided because we required clarification from the requester.

Case reference FOI2025/00218

Received 2 March 2025

Published 5 May 2025

Request

We are a group of doctors from the Royal London Hospital carrying out a systematic review on adverse mental health side effects from hormones and hormone blockers used for management of endometriosis pain. We are contacting you at the medicines and healthcare products regulatory agency because many of our endometriosis patients in clinic report depression and anxiety from these medications, but this is not borne out by the body of research. We are exploring why this may be. Please can you help us by answering these questions: - does your reporting scheme invite the report of side effects of medications that are used for indications outside their license (such as combined pill for endometriosis) - do you have a body of reports of adverse mental health side effects from hormones and hormone blockers that you can share with us?

Response

see attached

Documents

• FOI2025_00218 redacted for publication.pdf (103.1 KB)

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