FOI release
Request of data on the MMRV vaccine.
Case reference FOI2026/00901
Received 13 August 2026
Published 1 October 2026
Request
Dear MHRA Freedom of Information Team, I am requesting information held by the MHRA concerning suspected adverse drug reactions reported through the Yellow Card Scheme for the MMRV vaccines Priorix-Tetra and ProQuad. I would like the information below for reports received from 1 January 2026 up to the latest date for which data are available. Please provide the following separately for: 1. Priorix-Tetra 2. ProQuad For each vaccine, please provide: • The total number of UK Yellow Card reports received. • The total number of suspected adverse reactions recorded within those reports. • The number of reports/reactions coded as: • Febrile convulsion • Febrile seizure • Convulsion • Seizure • Pyrexia/fever • Loss of consciousness • Encephalitis/encephalopathy • Meningitis • Other serious neurological adverse reactions • The number of reports classified as serious. • The number of reports involving hospitalisation. • The number of reports involving death, if any. • The number of reports in children aged approximately 12–24 months, if this age-specific information is held. I would also like to request the relevant Vaccine Analysis Print (VAP), or equivalent underlying Yellow Card data extract, for Priorix-Tetra and ProQuad covering the period above. Please provide the data in a form that allows the adverse-reaction terms to be identified separately, rather than providing only an overall adverse-event total. Please also state: • The precise reporting cut-off date used for the data. • Whether the figures represent UK reports only or include reports from outside the UK. • Whether a single Yellow Card report can contain multiple adverse-reaction terms and, if so, whether the reaction figures represent reports or individual reaction records. • Whether any reports have been excluded, for example because they were duplicates. • Whether the data include reports submitted by members of the public as well as healthcare professionals and pharmaceutical companies. I understand that Yellow Card reports are reports of suspected adverse reactions and do not, by themselves, establish causation. I am therefore not asking MHRA to determine whether the vaccine caused any reported event. I am specifically requesting the number of reports/reactions recorded in the Yellow Card database. If any part of this request is considered too broad, please provide the information that can be released and advise which specific part would need to be narrowed, rather than treating the entire request as a refusal. If the requested information is already publicly available, please provide the specific URL, dataset, table or VAP containing the figures, rather than a general link to the Yellow Card website.
Response
See attached
Documents
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